Applications

The unique featurs of MPC-Polymer make it superior to protein-based reagents.

Bead Based Assays

Features

MPC-Polymer are fully chemically synthesized substances, therefore exhibiting little biohazardous risk and little lot-to-lot variation.

MPC-Polymer effectively suppresses lot-to-lot variation.

Advantages

Blocking Effect

MPC-Polymer effectively suppresses non specific adsorption of protein on microplate or magnetic beads.

This experiment shows a 50 % better performance compared to the common material BSA.

Figure 1: A MaxiSorp (Thermo Fisher Scientific) 8-well plate was blocked with 10-fold diluted MPC-Polymer (0,5 wt% final, diluted with PBS).

Protein Stabilization Effect

MPC-Polymer effectively stabilizes proteins on solid or liquid phase materials.

MPC-Polymer and its hydrated water surrounds proteins to optimize the hydrophobic balance, and suppresses denaturation, aggregation, and non-specific adsorption to inside wall of vessel.

This experiment shows a 50 % better performance compared to the common material BSA.

Figure 2: A anti-mouse IgG antibody was immobilzed on a MaxiSorp (Thermo Fisher Scientific) 8-well plate and afterwards blocked with 10-fold diluted MPC-Polymer (0,1 wt%).

Sensitizing Effect (Latex Agglutination Test)

MPC-Polymer effectively improves the sensitivity of latex agglutination tests.

Figure 3: A latex agglutination test detecting CRP (C-reactive protein) was carried out to evaluate the performance of MPC-Polymer. The test was performed using 7070 automated analyzer (Hitachi). MPC-Polymer was added to the sample diluent and to the latex particle suspension (1 wt% final concentration).

Sensitizing Effect (Lateral Flow Test)

MPC-Polymer significantly improves the sensitivity of lateral flow tests.

Figure 4: A lateral flow test detecting SARS-CoV-2 IgM and IgG antibody was carried out using a combination of two MPC-Polymers in the final concentration 0,75 wt% in the buffer solution.

Product Line

We recommend to choose for the initial evaluation MPC-Polymer according to application and purpose (below table).

We offer a wide range of MPC-Polymers with various physical properties. In some cases a combination of two or more different MPC-Polymers are necessary. We are happy to find out your best MPC-Polymer (combination) to meet your needs.